The Air Force estimates that Wright-Patterson’s annual economic impact on the Dayton region is .1 billion.Ohio had three city-regions in the top 30 biotech locations in the country, with Cleveland-Akron ranked #20, Columbus #22, and Cincinnati #28.

Defense systems play a smaller role in the industry.

Ohio corporations were awarded around $5.5 billion of United States Department of Defense procurements.

The top five states ranked with the lowest effective tax rate on new investment are: (1) Maine (3.0%); (2) Oregon (3.8%); (3) Ohio (4.4%); (4) Wisconsin (4.5%); and (5) Illinois (4.6%).

Ohio is considered a center of science and industry, with museums dedicated to such in Columbus, COSI, the Great Lakes Science Center in Cleveland, the Imagination Station in Toledo, and the Boonshoft Museum of Discovery in Dayton.

In 2009, Governor Ted Strickland designated Dayton as Ohio's aerospace innovation hub, the first such technology hub in the state.

GE Aviation, headquartered in Evendale, is a major manufacturer of aircraft engines globally.

RTI International Metals's location in Niles produces titanium used in every France-based Airbus aircraft.

RTI was originally headquartered in Niles before moving to Pittsburgh in the 21st century, while Airbus has invested .3 billion in the state.

In 2013, Ohio was ranked in the top ten states for best business climate by Site Selection magazine, based on a business-activity database.