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First, 2 subcommittee members reviewed the titles and abstracts of references identified for each key question.The epidemiologist provided a deciding vote when required.
Articles selected at this stage were mapped back to the relevant main topic in the outline.
Subcommittee members were then assigned to writing teams that evaluated the evidence quality for selected topics and generated appropriate KASs in accordance with an AAP grading matrix (see Fig 1 and the detailed discussion in the forthcoming technical report).
Next, 2 subcommittee members and the epidemiologist conducted full-text reviews of the selected articles.
Although many subcommittee members have extensively published articles on topics covered in this guideline, articles were not preferentially selected on the basis of authorship.
The subcommittee epidemiologist created a detailed content outline, which was reviewed and approved by the subcommittee.
The outline contained a list of primary and secondary topics generated to guide a thorough literature search and meet the goal of providing an up-to-date systemic review of the literature pertaining to the diagnosis, management, and treatment of pediatric HTN as well as the prevalence of pediatric HTN and its associated comorbidities.Information on the prevalence of high blood pressure (BP) in children is largely derived from data from the NHANES and typically is based on a single BP measurement session.These surveys, conducted since 1988, indicate that there has been an increase in the prevalence of childhood high BP, including both HTN and elevated BP.In addition to the 30 KASs listed above, this guideline also contains 27 additional recommendations that are based on the consensus expert opinion of the subcommittee members.These recommendations, along with their locations in the document, are listed in Table 2.(See Table 1 for a complete list of KASs.)A detailed description of the methodology used to conduct the literature search and systematic review for this clinical practice guideline will be included in the forthcoming technical report.